Citizens of Science

In our quest to invent life-transforming medicines for people with serious diseases, we encourage our colleagues to publish their research in leading scientific journals. This page is intended for U.S. audiences only.

The links on this page are not affiliated with Regeneron Pharmaceuticals, Inc. Links to sites outside of Regeneron are provided as a resource to the viewer. Regeneron accepts no responsibility for the content of linked sites.

Featured Publications

Aging

The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

Published in Cell Rep. 2025 Mar 6;44(3):115403. doi: 10.1016/j.celrep.2025.115403. Online ahead of print.

Genetics

Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings

Published in Elife. 2024 Dec 13;12:RP90419. doi: 10.7554/eLife.90419.

Metabolic Stability and Targeted Delivery of Oligonucleotides: Advancing RNA Therapeutics Beyond The Liver

Published in J Med Chem. 2025 Jan 8. doi: 10.1021/acs.jmedchem.4c02528. Online ahead of print.

Immunology & Inflammation

Structural characterization of two γδ TCR/CD3 complexes

Published in Nat Commun. 2025 Jan 2;16(1):318. doi: 10.1038/s41467-024-55467-5.

The IL-4-IL-4Rα axis modulates olfactory neuroimmune signaling to induce loss of smell

Published in Allergy. 2024 Oct 17. doi: 10.1111/all.16338. Online ahead of print.

CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo

Published in Sci Transl Med. 2025 Mar 26;17(791):eado9371. doi: 10.1126/scitranslmed.ado9371. Epub 2025 Mar 26.

Infectious Diseases

Monoclonal antibodies against the spike protein alter the endogenous humoral response to SARS-CoV-2 vaccination and infection

Published in Sci Transl Med. 2024 Nov 6;16(772):eadn0396. doi: 10.1126/scitranslmed.adn0396. Epub 2024 Nov 6.

Obesity, Muscle & Metabolism

Hepatic PKA Mediates the Liver and Pancreatic Alpha-Cell Crosstalk

Published in Diabetes. 2025 Mar 17:db240958. doi: 10.2337/db24-0958. Online ahead of print.

Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes

Published in Nat Commun. 2024 Nov 12;15(1):9776. doi: 10.1038/s41467-024-54124-1.

Oncology

Translational findings support regimen selection for first-in-human study of ubamatamab (MUC16 × CD3 bispecific antibody) in patients with recurrent ovarian cancer

Published in Clin Transl Sci. 2024 Dec;17(12):e70082. doi: 10.1111/cts.70082.