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1993 Publications

A single intramesencephalic injection of brain-derived neurotrophic factor induces persistent rotational asymmetry in rats
Shults CW, Matthews RT, Altar CA, Hill LR, Langlais PJ
Exp Neurol
125(2):183-94
Alternative forms of rat TrkC with different functional capabilities.
Valenzuela DM, Maisonpierre PC, Glass DJ, Rojas E, Nunez L, Kong Y, Gies DR, Stitt TN, Ip NY, Yancopoulos GD
Neuron
10:963-974
Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection
Morse JK, Wiegand SJ, Anderson K, You Y, Cai N, Carnahan J, Miller J, DiStefano PS, Altar CA, Lindsay RM, Alderson R
J Neurosci.
13(10):4146-56
Characterization and topography of high-affinity 125I-Neurotrophin-3 binding to mammalian brain
Altar CA, Criden MR, Lindsay RM, DiStefano PS.
Journal of Neuroscience
13(2):733- 743
Ciliary neurotrophic factor and its receptor complex
Ip NY, Yancopoulos GD
Progr Growth Factor Res
4:139-155
Ciliary neurotrophic factor maintains motoneurons and their target muscles in developing rats
Forger NG, Roberts SL, Wong V, Breedlove SM
J Neurosci
13(11):4720-6
Ciliary neurotrophic factor maintains the pluripotentiality of embryonic stem cells
Conover JC, Ip NY, Poueymirou WT, Bates B, Goldfarb MP, DeChiara TM, Yancopoulos GD
Development
119(3):559-65
Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component
Stahl N, Davis S, Wong V, Taga T, Kishimoto T, Ip NY, Yancopoulos GD
J Biol Chem
268(11):7628-31
Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF
Ip NY, Li Y, Yancopoulos GD, Lindsay RM
J Neurosci
13(8):3394-405
Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family
Maisonpierre PC, Goldfarb M, Yancopoulos GD, Gao G
Oncogene
8(6):1631-7
Ehk-1 and Ehk-2: two novel members of the Eph receptor-like tyrosine kinase family with distinctive structures and neuronal expression
Maisonpierre PC, Barrezueta NX, Yancopoulos GD
Oncogene
8(12):3277-88
Exchange of a single amino acid interconverts the specific activity and gel mobility of human and rat ciliary neurotrophic factors
Panayotatos N, Radziejewska E, Acheson A, Pearsall D, Thadani A, Wong V
J Biol Chem
268(25):19000-19003
Heterodimers of the neurotrophic factors: formation, isolation, and differential stability.
Radziejewski C, Robinson RC.
Biochemistry
32(48):13350-13356
Immunological relationships of NGF, BDNF, and NT-3: recognition and functional inhibition by antibodies to NGF
Murphy RA, Acheson A, Hodges R, Haskins J, Richards C, Reklow E, Chlumecky V, Barker PA, Alderson RF, Lindsay RM
J Neurosci
13(7):2853-62
Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain
Ip NY, Wiegand SJ, Morse J, Rudge JS
Eur J Neurosci
5(1):25-33
Investigations on the Structure-Function Relationship of Neurotrophins
Suter, U, Drinkwater, CC, Heymach, JV Jr., Lindsay RM, Shooter, EM
Neurotrophic Factors Taniguchi Symposia on Brain Sciences No. 15
27-34
Neural induction by the secreted polypeptide noggin
Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM
Science
262(5134):713-8
Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture.
Hory-Lee F, Russell M, Lindsay RM, Frank E.
Neurobiology
90:2613- 2617
Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion.
Ibanez CF, Ernfors P, Timmusk T, Ip NY, Arenas E, Yancopoulos GD, Persson H.
Development
117:1345-1353
Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF.
Lohof AM, Ip NY, Poo MM.
Nature
363:350-353
Proto-oncogenes and signaling processes in neural tissues
Sudol M, Grant SG, Maisonpierre PC
Neurochem Int
22 (4):369-384
Receptors and signaling pathways of Ciliary Neurotrophic Factor and the neurotrophins
Ip NY, Yancopoulos GD
Sem Neuro
5:249-257
Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses
Davis S, Aldrich TH, Ip NY, Stahl N, Scherer S, Farruggella T, DiStefano PS, Curtis R, Panayotatos N, Gascan H, Chevalier S, Yancopoulos GD
Science
259:1736-1739
Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury
Curtis R, Adryan KM, Zhu Y, Harkness PJ, Lindsay RM, DiStefano PS
Nature
365(6443):253-5
The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development
Ip NY, McClain J, Barrezueta NX, Aldrich TH, Pan L, Li Y, Wiegand SJ, Friedman B, Davis S, Yancopoulos GD.
Neuron
10:89-102
The molecular biology of the CNTF receptor
Davis S, Yancopoulos GD
Curr Opinion Cell Biol
5:281-285
The neurotrophins and their receptors
Glass DJ, Yancopoulos GD
Trends in Cell Biol
3:262-268
The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons.
Wong V, Arriaga R, Ip NY, Lindsay RM.
Eur J Neurosci
5:466-474
The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease
Lindsay RM, Altar CA, Cedarbaum JM, Hyman C, Wiegand SJ
Exp Neurol
124(1):103-18