Peer Review of Research Assures Standards of Quality
1995 Publications
| A BDNF autocrine loop in adult sensory neurons prevents cell death Acheson A, Conover JC, Fandl JP, DeChiara TM, Russell M, Thadani A, Squinto SP, Yancopoulos GD, Lindsay RM 374(6521):450-3 374 |
| A Phase I Study of Recombinant Human Ciliary Neurotropic Factor (rHCNTF) in Patients with Amyotrophic Lateral Sclerosis ALS CNTF Treatment Study (ACTS) Phase I-II Study Group Clinical Neuropharmacology 18/6:515-532 |
| Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein Gard AL, Burrell MR, Pfeiffer SE, Rudge JS, Williams WC 2nd Development 121(7):2187-97 |
| Axons, Schwann cells, and neurotrophic factors Friedman, B, Wong, V, Lindsay, RM The Neuroscientist 1:129-199 |
| BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons. Friedman B, Kleinfeld D, Ip NY, Verge VM, Moulton R, Boland P, Zlotchenko E, Lindsay RM, Liu L. Journal of Neuroscience 15(2):1044-1056 |
| BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. Siuciak JA, Wong V, Pearsall D, Wiegand SJ, Lindsay RM. European Journal of Neuroscience 7:663-670 |
| Brain-derived neurotrophic factor and neurotrophin-4/5 modify neurotransmitter-related gene expression in the 6-hydroxydopamine-lesioned rat striatum Sauer H, Wong V, Bjorklund A. Neuroscience 65:927-933 |
| Changes in neurotrophic factor expression and receptor activation following exposure of hippocampal neuron/astrocyte cocultures to kainic acid Rudge JS, Pasnikowski EM, Holst P, Lindsay RM. J. Neurosci. 15(10):6856-6867 |
| Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE Jr, Yancopoulos GD Science 267(5202):1349-53 |
| Ciliary neurotrophic factor arrests muscle and motoneuron degeneration in androgen-insensitive rats Forger NG, Wong V, Breedlove SM J Neurobiol. 28(3):354-62 |
| Ciliary neurotrophic factor inhibits brain and peripheral tumor necrosis factor production and, when coadministered with its soluble receptor, protects mice from lipopolysaccharide toxicity Benigni F, Villa P, Demitri MT, Sacco S, Sipe JD, Lagunowich L, Panayotatos N, Ghezzi P Mol Med 1(5):568-75 |
| Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing McDonald NQ, Panayotatos N, Hendrickson WA EMBO J 14(12):2689-99 |
| Cultured basal forebrain cholinergic neurons from postnatal rats show both overlapping and non-overlapping responses to the neurotrophins. Nonomura T, Nishio C, Lindsay RM, Hatanaka H Brain Res. 683(1):129-39 |
| Designer cytokines: targeting actions to cells of choice Economides AN, Ravetch JV, Yancopoulos GD, Stahl N. Science 270:1351-1353 |
| Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors Anderson KD, Alderson RF, Altar CA, DiStefano PS, Corcoran TL, Lindsay RM, Wiegand SJ. J. Comp. NeuroL 357:296-317 |
| Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins Curtis R, Adryan KM, Stark JL, Park JS, Compton DL, Weskamp G, Huber LJ, Chao MV, Jaenisch R, Lee KF, et al. Neuron 14:1201-1211 |
| Effects of BDNF on dopaminergic, serotonergic, and GABAergic neurons in cultures of human fetal ventral mesencephalon Spenger C, Hyman C, Studer L, Egli M, Evtouchenko L, Jackson C, Dahl-Jorgensen A, Lindsay RM, Seiler RW. Exp. Neurol. 133:50-63 |
| Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease Ikeda K, Klinkosz B, Greene T, Cedarbaum JM, Wong V, Lindsay RM, Mitsumoto H. Ann Neurol. 37:505-511 |
| Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling Ryden M, Murray-Rust J, Glass D, Ilag LL, Trupp M, Yancopoulos GD, McDonald NQ, Ibanez CF EMBO J. 14:1979-1990 |
| Histometric effects of ciliary neurotrophic factor in wobbler mouse motor neuron disease Ikeda K, Wong V, Holmlund TH, Greene T, Cedarbaum JM, Lindsay RM, Mitsumoto H Ann Neurol. 37:47-54 |
| Identification of mammalian noggin and its expression in the adult nervous system Valenzuela DM, Economides AN, Rojas E, Lamb TM, Nunez L, Jones P, Lp NY, Espinosa R 3rd, Brannan CI, Gilbert DJ, et al J Neurosci 15(9):6077-84 |
| Identification of new oligodendrocyte- and myelin-specific genes by a differential screening approach. Schaeren-Wiemers N, Schaefer C, Valenzuela DM, Yancopoulos GD, Schwab ME. J Neurochem. 65:10-22 |
| IL6, IL11, LIF, OSM, Cardiotrophin-1 and CNTF: An Example of a Cytokine Family Sharing Signal Transducing Receptor Components Stahl N, Yancopoulos GD Cytokines and Growth Factors in Health and Disease, (JAI Press, Inc.) 2B:767-799 |
| Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system Berhow MT, Russell DS, Terwilliger RZ, Beitner-Johnson D, Self DW, Lindsay RM, Nestler EJ. Neuroscience 68:969-979 |
| Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines Panayotatos N, Radziejewska E, Acheson A, Somogyi R, Thadani A, Hendrickson WA, McDonald NQ. J Biol Chem 270:14007-14014 |
| Mice lacking the CNTF receptor, unlike mice lacking CNTF, Exhibit Profound Motor Neuron Deficits at Birth DeChiara TM, Vejsada R, Poueymirou WT, Acheson A, Suri C, Conover JC, Friedman B, McClain J, Pan L, Stahl N, Ip NI, Kato A, Yancopoulos GD Cell 83:313-22. |
| Naturally occurring tyrosine kinase inserts block high affinity binding of phospholipase C gamma and Shc to TrkC and neurotrophin-3 signaling Guiton M, Gunn-Moore FJ, Glass DJ, Geis DR, Yancopoulos GD, Tavare JM. J Biol Chem 270:20384-20390 |
| Neuron-saving schemes Lindsay RM Nature 373:289-290 |
| Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4 Conover JC, Erickson JT, Katz DM, Bianchi LM, Poueymirou WT, McClain J, Pan L, Helgren M, Ip NY, Boland P, Friedman B, Wiegand S, Vejsada R, Kato AC, DeChiara TM, Yancopoulos GD Nature 375:235-238 |
| Neurotrophic factors and their receptors Ip NY, Yancopoulos GD. Prog Brain Res 105:189-195 |
| Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo Ilag LL, Curtis R, Glass D, Funakoshi H, Tobkes NJ, Ryan TE, Acheson A, Lindsay RM, Persson H, Yancopoulos GD, DiStefano PS, Ibanez CF Proc Natl Acad Sci U S A 92:607-611 |
| Potential therapeutic use of BDNF or NT-4/5 in Parkinson’s and Alzheimer’s diseases Altar CA, Alderson RF, Anderson KD, Hyman C, Wiegand SJ, Lindsay RM Adv in Behav Biol 44:611-61 |
| Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease Anand P, Parrett A, Martin J, Zeman S, Foley P, Swash M, Leigh PN, Cedarbaum JM, Lindsay RM, Williams-Chestnut RE, et al. Nature Medicine 1:168-172 |
| Specificity, synergy and autocrine roles of the neurotrophins and CNTF Lindsay RM Life and Death in the Nervous System Elsevier Science 363-378 |
| STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase Boulton TG, Zhong Z, Wen Z, Darnell JE Jr, Stahl N, Yancopoulos GD Proc. Natl. Acad. Sci. USA 92:6915-6919 |
| The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases Stitt TN, Conn G, Gore M, Lai C, Bruno J, Radziejewski C, Mattsson K, Fisher J, Gies DR, Jones PF, Masiakowski P, Ryan TE, Tobkes NJ, Chen DH, DiStefano PS, Long GL, Basilico C, Goldfarb M, Lemke G, Glass DJ, Yancopoulos GD Cell 80:661-670 |
| The Pharmacokenetics of Subcutaneously Administered Recombinant Human Ciliary Neurotrophic Factor (rHCNTF) in patients with Amyotrophic Lateral Sclerosis: Relation to Parameters of the Acute-Phase Response ALS CNTF Treatment Study (ACTS) Phase I-II Study Group Clinical Neuropharmacology 18/6: 500-514 |