Peer Review of Research Assures Standards of Quality

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2003 Publications

Activation of the hypothalamic arcuate nucleus predicts the anorectic actions of ciliary neurotrophic factor and leptin in intact and gold thioglucose-lesioned mice.
Anderson KD, Lambert PD, Corcoran TL, Murray JD, Thabet KE, Yancopoulos GD, Wiegand SJ
J Neuroendocrinol
15(7):649-60
Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases
Harfouche R, Gratton JP, Yancopoulos GD, Noseda M, Karsan A, Hussain SN
FASEB J
17(11):1523-5
Angiopoietin-1 and pulmonary hypertension: cause or cure?
Rudge JS, Thurston G, Yancopoulos GD
Circ Res.
92(9):947-9
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Davis S, Papadopoulos N, Aldrich TH, Maisonpierre PC, Huang T, Kovac L, Xu A, Leidich R, Radziejewska E, Rafique A, Goldberg J, Jain V, Bailey K, Karow M, Fandl J, Samuelsson SJ, Ioffe E, Rudge JS, Daly TJ, Radziejewski C, Yancopoulos GD
Nat Struct Biol.
10(1):38-44
Bone morphogenetic proteins, their antagonists, and the skeleton
Canalis E, Economides AN, Gazzerro E
Endocr Rev.
24(2):218-35
Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice
Sleeman MW, Garcia K, Liu R, Murray JD, Malinova L, Moncrieffe M, Yancopoulos GD, Wiegand SJ
Proc Natl Acad Sci U S A
100(24):14297-302
Cytokine traps: multi-component, high-affinity blockers of cytokine action
Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler-Stec EM, Hartnett C, Pyles EA, Xu X, Daly TJ, Young MR, Fandl JP, Lee F, Carver S, McNay J, Bailey K, Ramakanth S, Hutabarat R, Huang TT, Radziejewski C, Yancopoulos GD, Stahl N
Nat Med
9(1):47-52
Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm
Williams SE, Mann F, Erskine L, Sakurai T, Wei S, Rossi DJ, Gale NW, Holt CE, Mason CA, Henkemeyer M
Neuron
39(6):919-35
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis
Valenzuela DM, Murphy AJ, Frendewey D, Gale NW, Economides AN, Auerbach W, Poueymirou WT, Adams NC, Rojas J, Yasenchak J, Chernomorski R, Boucher M, Elsasser AL, Esau L, Zheng J, Griffiths JA, Wang X, Su H, Xue Y, Dominguez MG, Noguera I, Torres R, Macdonald LE, Stewart AF, DeChiara TM, Yancopoulos GD
Nat Biotechnol
21(6):652-9
In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification
Glaser DL, Economides AN, Wang L, Liu X, Kimble RD, Fandl JP, Wilson JM, Stahl N, Kaplan FS, Shore EM
J Bone Joint Surg Am
85-A(12):2332-42
Molecular mechanisms modulating muscle mass
Glass DJ
Trends Mol Med
9(8): 344-350
Noggin arrests stromal cell differentiation in vitro
Gazzerro E, Du Z, Devlin RD, Rydziel S, Priest L, Economides AN, Canalis E
Bone
32(2):111-9
p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop
Ongusaha PP, Kim JI, Fang L, Wong TW, Yancopoulos GD, Aaronson SA, Lee SW
EMBO J
22(6):1289-1301
Regression of established tumors and metastases by potent vascular endothelial growth factor blockade
Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O'Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ
Proc Natl Acad Sci U S A
100(13):7785-90
Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
Thurston G
Cell Tissue Res
314(1):61-8
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
Glass DJ
Nat Cell Biol
5(2): 87-90
Skeletal overexpression of noggin results in osteopenia and reduced bone formation
Devlin RD, Du Z, Pereira RC, Kimble RB, Economides AN, Jorgetti V, Canalis E
Endocrinology.
144(5):1972-8
Structural basis of BMP signaling inhibition by Noggin, a novel twelve-membered cystine knot protein
Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Baban K, Affolter M, Vale WW, Belmonte JC, Choe S
J Bone Joint Surg Am
85-A Suppl 3:52-
The BMP antagonist noggin regulates cranial suture fusion
Warren SM, Brunet LJ, Harland RM, Economides AN, Longaker MT
Nature
422(6932):625-9
Transgenic delivery of VEGF to the mouse skin leads to an inflammatory condition resembling human psoriasis
Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS
Blood
102(1):161-8
Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model.
Byrne AT, Ross L, Holash J, Nakanishi M, Hu L, Hofmann JI, Yancopoulos GD, Jaffe RB
Clin Cancer Res
15;9(15):5721-8
VEGF-Dependent Conjunctivalization of the Corneal Surface
Joussen AM, Poulaki V, Mitsiades N, Stechschulte SU, Kirchhof B, Dartt DA, Fong GH, Rudge J, Wiegand SJ, Yancopoulos GD, Adamis AP
Invest Ophthalmol Vis Sci
44(1):117-123
VEGF-TRAPR1R2 suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier.
Saishin Y, Saishin Y, Takahashi K, Silva RL, Hylton D, Rudge JS, Wiegand SJ, Campochiaro PA.
J Cell Physiol.
195(2):241-8