Citizens of Science
In our quest to invent life-transforming medicines for people with serious diseases, we encourage our colleagues to publish their research in leading scientific journals. This page is intended for U.S. audiences only.
Featured Publications
Genetics
Genetic risk factors for COVID-19 and influenza are largely distinctPublished in Nat Genet. 2024 Aug 5. doi: 10.1038/s41588-024-01844-1. Online ahead of print.
A deep catalogue of protein-coding variation in 983,578 individualsPublished in Nature. 2024 May 20. doi: 10.1038/s41586-024-07556-0. Epub ahead of print.
Hematology
Peripheral human red blood cell development in human immune system mouse model with heme oxygenase-1 deficiencyPublished in Blood Adv. 2024 Sep 30:bloodadvances.2023011754. doi: 10.1182/bloodadvances.2023011754. Online ahead of print.
Immunology & Inflammation
Designing meaningful continuous representations of T cell receptor sequences with deep generative modelsPublished in Nat Commun. 2024 May 20;15(1):4271. doi: 10.1038/s41467-024-48198-0.
Infectious Diseases
Population Pharmacokinetics of Casirivimab and Imdevimab in Pediatric and Adult Non-Infected Individuals, Pediatric and Adult Ambulatory or Hospitalized Patients or Household Contacts of Patients Infected with SARS-COV-2Published in Pharm Res. 2024 Sep 18. doi: 10.1007/s11095-024-03764-5. Online ahead of print.
Oncology
LTβR Agonism Promotes Anti-Tumor Immune Responses via Modulation of the Tumor MicroenvironmentPublished in Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-2716. Online ahead of print.
Technology
Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mappingPublished in J Pharm Biomed Anal. 2024 Aug 26;251:116452. doi: 10.1016/j.jpba.2024.116452. Online ahead of print.
Immunology & Inflammation
Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 InflammationPublished in N Engl J Med. 2024 May 20. doi: 10.1056/NEJMoa2401304.
Dupilumab Efficacy in Children With Type 2 Asthma Receiving High/Medium-Dose ICS (VOYAGE)Published in J Allergy Clin Immunol Pract. 2024 Aug 27:S2213-2198(24)00858-4. doi: 10.1016/j.jaip.2024.08.038. Online ahead of print.
Infectious Diseases
Patient-Reported Outcomes in COVID-19 Treatment with Monoclonal Antibodies Reveal Benefits in Return to Usual ActivitiesPublished in Infect Dis Ther. 2024 Jul 3. doi: 10.1007/s40121-024-01013-1. Online ahead of print.
Obesity, Muscle & Metabolism
Characterization of flare-ups and impact of Garetosmab in adults with Fibrodysplasia Ossificans Progressiva: a post hoc analysis of the randomized, double-blind, placebo-controlled LUMINA-1 trialPublished in J Bone Miner Res. 2024 Aug 31:zjae140. doi: 10.1093/jbmr/zjae140. Online ahead of print.
Oncology
Quality of life in cemiplimab-treated patients with locally advanced basal cell carcinoma in a Phase II clinical trialPublished in Future Oncol. 2024 Jul 29:1-10. doi: 10.1080/14796694.2024.2358670. Online ahead of print.
Rare Diseases
Pozelimab for CHAPLE disease: results from in-trial interviews and clinical outcome assessmentsPublished in Orphanet J Rare Dis. 2024 Aug 8;19(1):290. doi: 10.1186/s13023-024-03277-9.