Scientific Publications Citizens of Science
In our quest to invent life-transforming medicines for people with serious diseases, we encourage our colleagues to publish their research in leading scientific journals.
Featured Publications
- Early-Stage Research
- Clinical Research
Genetics
Genetic risk factors for COVID-19 and influenza are largely distinct
Published in Nat Genet. 2024 Aug 5. doi: 10.1038/s41588-024-01844-1. Online ahead of print.
A deep catalogue of protein-coding variation in 983,578 individuals
Published in Nature. 2024 May 20. doi: 10.1038/s41586-024-07556-0. Epub ahead of print.
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone
Published in Nature. 2024 Sep 11. doi: 10.1038/s41586-024-07903-1. Online ahead of print.
Hematology
Peripheral human red blood cell development in human immune system mouse model with heme oxygenase-1 deficiency
Published in Blood Adv. 2024 Sep 30:bloodadvances.2023011754. doi: 10.1182/bloodadvances.2023011754. Online ahead of print.
Immunology & Inflammation
Designing meaningful continuous representations of T cell receptor sequences with deep generative models
Published in Nat Commun. 2024 May 20;15(1):4271. doi: 10.1038/s41467-024-48198-0.
Infectious Diseases
Population Pharmacokinetics of Casirivimab and Imdevimab in Pediatric and Adult Non-Infected Individuals, Pediatric and Adult Ambulatory or Hospitalized Patients or Household Contacts of Patients Infected with SARS-COV-2
Published in Pharm Res. 2024 Sep 18. doi: 10.1007/s11095-024-03764-5. Online ahead of print.
Oncology
LTβR Agonism Promotes Anti-Tumor Immune Responses via Modulation of the Tumor Microenvironment
Published in Cancer Res. 2024 Aug 13. doi: 10.1158/0008-5472.CAN-23-2716. Online ahead of print.
Technology
Distinct chemical degradation pathways of AAV1 and AAV8 under thermal stress conditions revealed by analytical anion exchange chromatography and LC-MS-based peptide mapping
Published in J Pharm Biomed Anal. 2024 Aug 26;251:116452. doi: 10.1016/j.jpba.2024.116452. Online ahead of print.
Immunology & Inflammation
Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation
Published in N Engl J Med. 2024 May 20. doi: 10.1056/NEJMoa2401304.
Dupilumab Efficacy in Children With Type 2 Asthma Receiving High/Medium-Dose ICS (VOYAGE)
Published in J Allergy Clin Immunol Pract. 2024 Aug 27:S2213-2198(24)00858-4. doi: 10.1016/j.jaip.2024.08.038. Online ahead of print.
Infectious Diseases
Patient-Reported Outcomes in COVID-19 Treatment with Monoclonal Antibodies Reveal Benefits in Return to Usual Activities
Published in Infect Dis Ther. 2024 Jul 3. doi: 10.1007/s40121-024-01013-1. Online ahead of print.
Effect of timing of casirivimab and imdevimab administration relative to mRNA-1273 COVID-19 vaccination on vaccine-induced SARS-CoV-2 neutralising antibody responses: a prospective, open-label, phase 2, randomised controlled trial
Published in Lancet Infect Dis. 2024 Sep 2:S1473-3099(24)00421-3. doi: 10.1016/S1473-3099(24)00421-3. Online ahead of print.
Obesity, Muscle & Metabolism
Characterization of flare-ups and impact of Garetosmab in adults with Fibrodysplasia Ossificans Progressiva: a post hoc analysis of the randomized, double-blind, placebo-controlled LUMINA-1 trial
Published in J Bone Miner Res. 2024 Aug 31:zjae140. doi: 10.1093/jbmr/zjae140. Online ahead of print.
Oncology
Quality of life in cemiplimab-treated patients with locally advanced basal cell carcinoma in a Phase II clinical trial
Published in Future Oncol. 2024 Jul 29:1-10. doi: 10.1080/14796694.2024.2358670. Online ahead of print.
Rare Diseases
Pozelimab for CHAPLE disease: results from in-trial interviews and clinical outcome assessments
Published in Orphanet J Rare Dis. 2024 Aug 8;19(1):290. doi: 10.1186/s13023-024-03277-9.